Curriculum Vitae

Education

Savitribai Phule Pune University, Department of Zoology

Ph.D., Zoology

Advisors: Prof. Saroj Ghaskadbi & Dr. Yogesh Shouche

Thesis: “Molecular profiling and comparative analysis of gut microbiome of diabetic and non-diabetic individuals.”

Pune

2012-2017

University of Pune

M. Sc. in Microbiology

Pune

2004-2006

University of Pune

B. Sc. in Microbiology

Pune

1999-2002

Research Experience

Jacobs Lab & Goodman-Luskin Microbiome Center, UC Los Angeles

Associate Project Scientist

  • Implementing and refining sequence-based microbiome assays.

  • Assisting Microbiome Core functionalities.

Los Angeles

Aug 2023 - Present

Center for Microbiome Innovation, University of California San Diego

Postdoctoral fellow

  • Contributed to the industry-sponsored project (EMD-Serono-Millipore and  Pfizer) to deplete the host DNA from the total metagenomic DNA.

  • Contributed to developing a miniaturized protocol for surveying SARS-CoV-2 from wastewater using metatranscriptomics and advanced liquid handling robots – SPT LabTech Mosquito, Labocyte Echo.

San Diego

Jan 2021 - Aug 2023

University of Nevada, Las Vegas

Postdoctoral fellow

  • Applied an integrated omics approach to assess the effect of diets on the relapse of Clostridium difficile infections.

  • Demonstrated the antibiotics-associated loss of C. difficile competitors due to high-fat/high-protein diets and its association with C. difficile proliferation and virulence.

  • Characterized gut microbiota of endangered Mojave Desert pupfish (Cyprinodon species) and proposed its involvement in the paradoxical anaerobism observed in these fish.

Las Vegas

2018- 2021

Savitribai Phule Pune University, Department of Zoology

Ph.D. Student

  • Characterized healthy human gut microbiota of representative samples from the Indian population, leading to the identification of predominance of Prevotella and Megasphaera in Indian individuals.

  • Performed comparative meta-analysis and demonstrated the graded difference of the Indian gut microbial communities from the neighboring and other countries.

  • Provided evidence of the consolidated dysbiosis across the members of three domains of life in the gut of diabetic subjects.

Pune

2012-2017

National Centre for Cell Sciences

Other research work during my Ph.D.

  • Demonstrated a selective enrichment of Oxalate Metabolizing Bacterial Species (OMBS) in hyperoxaluria and the role of gut microbiota in oxalate homeostasis.

  • Used large-scale culture-dependent and culture-independent approaches and indicated potential bacterial pathogens in Rousettus leschenaultii guano

Pune

2012-2017

Teaching Experience

University of Nevada, Las Vegas

Course: General Microbiology (Biol 251)

Activities: Designed and delivered 20 lectures

Graded four assignments and in-class exercises; held regular one-on-one office hours

Las Vegas

2020, 2019, 2018 (Summer)

Department of Microbiology, Modern College of Arts, Science and Commerce

Assistant Professor (Ad-Hoc)

Courses: Microbial Taxonomy, Virology

Activities: Delivered lectures based on the syllabus designed by the University; managed laboratory sessions; conducted in-class exercises; held regular one-on-one office hours; planned visits to research institutes

Research:

  • Characterization of silver and gold nanoparticles produced by Fusarium species

  • Culturable diversity of two soccer fields’ soil samples

Pune

2016-2017

Department of Biochemistry, Fergusson College

Visiting Faculty

Course: Bioinformatics

Activities: Delivered lectures based on the syllabus designed by the University; managed laboratory sessions, conducted in-class exercises; held regular one-on-one office hours

Pune

2014-2016

Department of Microbiology, New Arts, Commerce & Science College

Assistant Professor

Courses: General Microbiology, Molecular Biology, Immunology, Microbial Taxonomy, Virology, Bioinstrumentation, Biostatistics, and Bioinformatics

Activities: Delivered lectures based on the syllabus designed by the University; managed laboratory sessions; conducted in-class exercises; held regular one-on-one office hours; integrated guest lectures; and planned visits to research institutes

Research:

  • Degradation of food colorants by intestinal bacteria

  • Exploration of Pseudomonas species as phosphate solubilizer, plant growth promoter, biocontrol agent, and pesticide degrader

  • Antimicrobial properties of Withania somnifera root extracts

  • Effect of solar radiations on the growth of food- and water-borne pathogens during the solar eclipse.

Ahmednagar

2006-2010

Selected Meeting Presentations

Talks and Seminars:

Delivered a seminar entitled – “Molecular profiling and comparative analysis of gut microbiome of diabetic and non-diabetic individuals” at the School of Life Science seminar series at UNLV, Las Vegas. September 21, 2018.

Delivered a seminar on – “Isolation and purification of biomolecules” at the Institute of Science, Mumbai, on November 06, 2017, during the National Eligibility Test/State Eligibility Test workshop.

Delivered a talk on ‘Sequence alignment and analysis’ at a State-level workshop on computational methods in life sciences at New Arts, Commerce, and Science College Ahmednagar, organized and sponsored by Savitribai Phule University Pune University, September 26, 2017.

Delivered a seminar on – “Biophysical Methods” at the Institute of Science, Mumbai, on December 02, 2011, during the National Eligibility Test/State Eligibility Test workshop.

Conferences and Symposia:

Bhute SS, Joshi S, Ghaskadbi S, Yajnik C, Shouche Y 2018. Presented poster at Manipulation of the Gut Microbiota for Metabolic Health (X3); Fairmont Banff Springs, Banff, Canada; March 4-8, 2018.

Attended the third meeting of Bergey’s International Society for Microbial Systematics (BISMiS) on Microbial Systematics and Metagenomics, organized jointly by BISMiS, Microbial Culture Collection, and the Association of Microbiologists of India on September 12 – 15, 2016.

Bhute SS, Joshi S, Ghaskadbi S, Yajnik C, Shouche Y. 2015. Presented poster at Cell-CHIN-Symposia: Human Immunity and the Microbiome in Health and Disease; at Hotel Bonaventure, Montreal, Canada; 27-29th Sep 2015.

Bhute SS, Joshi S, Ghaskadbi S, Yajnik C, Shouche Y. 2015. Presented poster at two days symposium on “Probiotics: from Bench to Community” Organized by Yakult India Microbiota and Probiotics Science Foundation at The Grand Hotel, New Delhi; March 07-08, 2015. 

Bhute SS, Joshi S, Ghaskadbi S, Yajnik C, Shouche Y. 2014. Presented poster at two days symposium on “Probiotics, Microbiome and Gut functions: Transforming Health and Well-being” Organized by Yakult India Microbiota and Probiotics Science Foundation; at The Eros Hotel, New Delhi; February 15-16, 2014. 

Attended the Symposium on ‘Microbes: Molecular Ecology and Systematics’ organized by Microbial Culture Collection and the Association of Microbiologists of India on September 11 and 12, 2012.

Workshops:

Conducted a hands-on tutorial on – “Analysis of 16S rRNA sequence data using QIIME” organized for teachers from undergraduate and postgraduate life sciences departments at the state-level workshop on techniques in molecular phylogenetic analysis, 5-8 January 2016 organized by the Department of Botany, Savitribai Phule Pune University, Pune.

Professional Services

Editorial Board Member:

BMC Microbiology, BioMed Research International

Peer Review:

Scientific Report, MDPI Diagnostics, International Journal of Obesity, Microbiological Research, Functional Ecology, Journal of Clinical Medicine, PLOS ONE, Water Research, AIMS Environmental Science, Current Science, Microbiological Research, Frontiers in Microbiology, Frontiers in Oncology, Frontiers in Cellular and Infection Microbiology, Frontiers in Ecology and Evolution, Frontiers in Medicine, and Bergey’s Manual of Systematic Bacteriology.

Grant Review: Graduate Women in Science